Chitohexaose 6HCl

Chitohexaose 6HCl - Names and Identifiers

Name	Chitohexaose Hexahydrochloride
Synonyms	Chitohexaose 6HCl Chitohexaose Hydrochloride Chitohexaose Hexahydrochloride O-2-Amino-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-amino-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-amino-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-amino-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-amino-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-amino-2-deoxy-D-glucose
CAS	41708-95-6

Chitohexaose 6HCl - Physico-chemical Properties

Molecular Formula	C36H68N6O25·6HCl
Molar Mass	1203.71
Boling Point	1298.9±65.0°C
Solubility	Can dissolve in water
Appearance	Powder
Storage Condition	2-8℃
MDL	MFCD00210263
Physical and Chemical Properties	The product is white to light yellow powdery or flocculent freeze-dried; odorless, non-irritating odor; hygroscopic.
Use	Used for the development of new products of oligosaccharides in the fields of medicine, food, aquaculture, modern agriculture, daily chemical industry and biochemical reagents; reference substance for the inspection and analysis of oligosaccharides and quality control; research on the preparation of oligosaccharides; research on the interaction between oligosaccharides and proteins; research on the structure-activity relationship and mechanism of action of oligosaccharides and other research fields of sugar chemistry and sugar biology.

Chitohexaose 6HCl - Uses and synthesis methods

overview

The hexasaccharide is a substance of the formula C36H68N6O25?6HCl, and the hexasaccharide is the product of partial degradation of chitosan.

Preparation process

from shrimp and crab shell chitin as raw material, by enzymatic degradation, chemical derivatization and column chromatography separation to obtain chitooligosaccharides, monomer standard, polymerization degree from 2 to 6.

application

Used for the development of new products of chitooligosaccharides in the fields of medicine, food, aquaculture, modern agriculture, daily chemical industry and biochemical reagents; reference substance for inspection and analysis of chitooligosaccharides and quality control; research on the preparation of oligosaccharides; research on the interaction between oligosaccharides and proteins; research on the structure-activity relationship and mechanism of action of oligosaccharides and other research fields of sugar chemistry and glycobiology. In addition, studies have found that hexasaccharide can also produce obvious tumor inhibition, and the effect is the strongest when the concentration is 10 mg /kg. Not only that, hexacose also showed good effect on inhibiting tumor metastasis. Hexamasaccharide can inhibit tumor angiogenesis by inhibiting the proliferation and migration of vascular endothelial cells, and has a very important application in the preparation of drugs to prevent angiogenesis.

Toxicity

Non-toxic.

Stability

Keep frozen for more than 3 years.

detection analysis

thin layer chromatography (TLC) analysis, high performance gel permeation chromatography (HPLC) analysis, electrospray mass spectrometry (ESI-MS) analysis.

References

[1] http://baike.baidu.com/link?url=XK7yzR3h0md6I9Kp-lEOIwPguSxoB7n8pQsv85HhPGHL7gsKNWir-MPAI2uzWYS6nbFhfOMAa61Fctb8DoED4cJgy3x3VIVzRtO5_dmOgF9LXS8j3ZSChE2qb_o5O4Vv

[2] Permission, Chen Junquan. Experimental study on the treatment of pterygium with hexacide [J]. Chinese Journal of Gerontology, 2012, 32(24).

[3] Du Yuguang, Xiong Chuannan, Wu Haige, et al. Application of hexasaccharide in the preparation of drugs for preventing angiogenesis [J]. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 2010.

Last Update：2024-04-09 20:52:54